Cupric sulfate ke letsoai le entsoeng ka ho phekola cupric oxide ka sulfuric acid.Sena se etsa likristale tse kholo, tse khanyang tse putsoa tse nang le limolek'hule tse hlano tsa metsi (CuSO4∙5H2O) hape e tsejoa e le blue vitriol.Letsoai la anhydrous le entsoe ka ho futhumatsa hydrate ho 150 °C (300 °F).